The biochemical effect of auromomycin on bacterial cells.
نویسندگان
چکیده
The mechanism of action of auromomycin was studied with intact cells of Bacillus subtilis. The antibiotic exhibited a preferential inhibition of DNA synthesis over RNA and protein syntheses. The strand scission of cellular DNA was induced by the drug, and DNA was degraded into acid-soluble fragments. The results suggested that DNA is the chemoreceptor of auromomycin.
منابع مشابه
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 32 7 شماره
صفحات -
تاریخ انتشار 1979